Combinatorial ‘library on bead’ approach to polymeric materials with vastly enhanced chiral recognition
Chemical Communications Pub Date: 1900-01-01 DOI: 10.1039/A806397D
Abstract
A general screening method for enantiomer recognition is introduced for the rapid preparation of novel chiral stationary phases for HPLC in which libraries of mixed chiral selectors are immobilized on polymer beads and the resulting chiral phases tested in the separation of racemic targets followed by deconvolution to afford an optimized separation medium.
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Journal Name:Chemical Communications
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CAS no.: 89640-58-4