Chemical Reaction-Induced Multi-molecular Polarization (CRIMP)?
Chemical Communications Pub Date: 2014-09-02 DOI: 10.1039/C4CC06199C
Abstract
Here we present a novel hyperpolarization method, Chemical Reaction-Induced Multi-molecular Polarization (CRIMP), which could be applied to the study of several in vivo processes simultaneously including glycolysis, TCA cycle, fatty acid synthesis and pH mapping. Through the use of non-enzymatic decarboxylation, we generate four hyperpolarized imaging agents from hyperpolarized 1,2-13C pyruvic acid.
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Journal Name：Chemical Communications
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CAS no.: 89640-58-4
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