Chemical introduction of the green fluorescence: imaging of cysteine cathepsins by an irreversibly locked GFP fluorophore?
Organic & Biomolecular Chemistry Pub Date: 2013-07-16 DOI: 10.1039/C3OB41341A
Abstract
An activity-based probe, containing an irreversibly locked GFP-like fluorophore, was synthesized and evaluated as an inhibitor of human cathepsins and, as exemplified with cathepsin K, it proved to be suitable for ex vivo imaging and quantification of cysteine cathepsins by SDS-PAGE.
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Journal Name：Organic & Biomolecular Chemistry
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CAS no.: 89640-58-4
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