Coenzyme biosynthesis: enzyme mechanism, structure and inhibition?

Natural Product Reports Pub Date: 2007-08-28 DOI: 10.1039/B703108B

Abstract

Covering: 1997 to 2007

This review highlights five key reactions in vitamin biosynthesis and in particular focuses on their mechanisms and inhibition and insights from structural studies. Each of the enzymes has the potential to be a target for novel antimicrobial agents.

Graphical abstract: Coenzyme biosynthesis: enzyme mechanism, structure and inhibition
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