A convenient and efficient C–OH bond activation, PdCl2(PPh3)2 catalyzed, C–C bond formation of tautomerizable quinolinones with the aid of BOP reagent and boronic acids?
RSC Advances Pub Date: 2014-08-12 DOI: 10.1039/C4RA05161K
Abstract
An efficient, highly chemoselective PdCl2(PPh3)2 catalyzed, C–C bond formation of tautomerizable quinolinones with various boronic acids via C–OH bond activation using benzotriazol-1-yloxytris(dimethylamino) phosphonium hexafluorophosphate (BOP) reagent in the presence of K2CO3/1,4-dioxane system under aqueous condition, leads to the formation of functionalized quinolines in excellent yields, which offers great utility advantages in the synthesis of interesting compounds.
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Journal Name：RSC Advances
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CAS no.: 89640-58-4
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