Catalytic reduction of amides to amines by electrophilic phosphonium cations via FLP hydrosilylation?
Chemical Communications Pub Date: 2016-09-13 DOI: 10.1039/C6CC06914B
Abstract
A catalytic methodology for the conversion of amides to amines is reported. Of the 25 examples described, 14 examples involve the reduction of N-trifluoroacetamides to the corresponding trifluoroethylamines. These reductions are achieved by catalytic hydrosilylation of the amide mediated by an electrophilic phosphonium cation (EPC) catalyst.
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Journal Name：Chemical Communications
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CAS no.: 89640-58-4
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