A copper catalyzed multicomponent cascade redox reaction for the synthesis of quinazolinones?
RSC Advances Pub Date: 2016-05-26 DOI: 10.1039/C6RA10997G
Abstract
A copper catalyzed multicomponent cascade redox reaction for the synthesis of various quinazolinones starting from easily available 2-bromobenzamides, benzylic alcohols and sodium azide as a nitrogen source has been developed. The reaction involves copper catalyzed azidation of 2-bromobenzamide via an SNAr reaction and oxidation of benzyl alcohol followed by sequential reduction–condensation–oxidation to produce quinazolinones.
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Journal Name：RSC Advances
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CAS no.: 89640-58-4
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