Catalytic, enantio- and diastereoselective synthesis of γ-butyrolactones incorporating quaternary stereocentres??

Chemical Communications Pub Date: 2012-05-23 DOI: 10.1039/C2CC32147E

Abstract

A new, highly enantio- and diastereoselective catalytic asymmetric formal cycloaddition of aryl succinic anhydrides and aldehydes which generates paraconic acid (γ-butyrolactone) derivatives is reported.

Graphical abstract: Catalytic, enantio- and diastereoselective synthesis of γ-butyrolactones incorporating quaternary stereocentres
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