Catalyst- and solvent-free approach to 2-arylated quinolines via [5 + 1] annulation of 2-methylquinolines with diynones?
RSC Advances Pub Date: 2018-01-25 DOI: 10.1039/C7RA12716B
Abstract
A novel route for the synthesis of 2-arylated quinolines through a [5 + 1] annulation directly from 2-methylquinolines and diynones under catalyst-free and solvent-free conditions was disclosed. This synthetic process was atom-economic, with good tolerance of a broad range of functional groups, and with great practical worth.
![Graphical abstract: Catalyst- and solvent-free approach to 2-arylated quinolines via [5 + 1] annulation of 2-methylquinolines with diynones](http://scimg.chem960.com/usr/1/C7RA12716B.jpg)
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Journal Name：RSC Advances
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CAS no.: 89640-58-4
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