A concise asymmetric total synthesis for structure elucidation of 5,6-secoiridoid from Incarvillea argute?
RSC Advances Pub Date: 2016-07-21 DOI: 10.1039/C6RA15153A
Abstract
A phytochemical investigation of the roots of Incarvillea arguta led to the isolation of secoarguterin (1), which is the first example of 5,6-secoiridoid. Its structure and absolute configuration was elucidated by extensive spectral analysis and total synthesis. Compound 1 showed moderate inhibition against human colon cancer cells HCT116 with an IC50 value of 28.72 μM.
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Journal Name：RSC Advances
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CAS no.: 89640-58-4
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