Azide–acetonitrile “click” reaction triggered by Cs2CO3: the atom-economic, high-yielding synthesis of 5-amino-1,2,3-triazoles?
RSC Advances Pub Date: 2015-07-13 DOI: 10.1039/C5RA12308A
Abstract
Medicinally important 5-amino-1,2,3-triazoles were synthesized using a novel Cs2CO3-catalyzed azide–acetonitrile[3 + 2]-cycloaddition. Aryl azides and aryl acetonitriles were employed in this transformation resulting in excellent yields with high regioselectivity.
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Journal Name：RSC Advances
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CAS no.: 89640-58-4
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