C(sp2)–H functionalization of aldehyde-derived hydrazones via a radical process
Organic & Biomolecular Chemistry Pub Date: 2018-02-05 DOI: 10.1039/C8OB00056E
Abstract
This review is focused on the recent advances in the C(sp2)–H functionalization of aldehyde-derived hydrazones via a radical process. Diverse substituted hydrazones including N-heterocycles are afforded under mild conditions with excellent selectivities. In general, an aminyl radical as the key intermediate is involved during the reaction process, and a broad reaction scope with good functional group tolerance can be observed. In some cases, a photocatalyst under visible light irradiation is involved, which initiates the radical reaction.
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Journal Name:Organic & Biomolecular Chemistry
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CAS no.: 89640-58-4