Bio-inspired enantioselective full transamination using readily available cyclodextrin??

RSC Advances Pub Date: 2017-01-16 DOI: 10.1039/C6RA27525G

Abstract

The mimics of vitamin B6-dependent enzymes that catalyzed an enantioselective full transamination in the pure aqueous phase have been realized for the first time through the establishment of a new “pyridoxal 5′-phosphate (PLP) catalyzed non-covalent cyclodextrin (CD)-keto acid inclusion complexes” system, and various optically active amino acids have been obtained.

Graphical abstract: Bio-inspired enantioselective full transamination using readily available cyclodextrin
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