Benzothiazole derivatives as substrates for alkaline phosphatase assay with fluorescence and chemiluminescence detection
Analyst Pub Date: DOI: 10.1039/AN9952001709
Abstract
Unique fluorogenic and chemiluminescence substrates for alkaline phosphatase (ALP), 2-(N-phenylphthalimidyl)benzothiazolyl-5-phosphate and 2-(2′,3′-dihydro-1′,4′-dionephthalazyl)benzothiazolyl-5-phosphate, respectively, that contain a highly fluorescent benzothiazole moiety as the fluorophore were synthesized and their applicabilities to the assay of ALP were examined. The chemiluminogenic substrate exhibited a linear chemiluminescence response to the amount of ALP in the range 0–20 pmol.
Recommended Literature
- [1] An ionic liquid-based synergistic extraction strategy for rare earths? Yingbo Li,Nada Mehio,Huizhou Liu,Sheng DaiGreen Chem., 2015,17, 2981-2993 10.1039/C5GC00360A
- [2] Achieving high-efficiency purely organic room-temperature phosphorescence materials by boronic ester substitution of phenoxathiine? Mengke Li,Xinyi Cai,Zhenyang Qiao,Wentao Xie,Liangying Wang,Nan Zheng,Shi-Jian SuChem. Commun., 2019,55, 7215-7218 10.1039/C9CC02648G
- [3] An ion-gating multinanochannel system based on a copper-responsive self-cleaving DNAzyme? Yang Chen,Di Zhou,Zheyi Meng,Jin ZhaiChem. Commun., 2016,52, 10020-10023 10.1039/C6CC03943J
- [4] An approach for correlating the structural and electrical properties of Zr4+-modified SrBi4Ti4O15/SBT ceramic Priyambada Nayak,Tanmaya Badapanda,Anil Kumar Singh,Simanchalo PanigrahiRSC Adv., 2017,7, 16319-16331 10.1039/C7RA00366H
- [5] An anti-leakage liquid metal thermal interface material Kaiyuan Huang,Wangkang Qiu,Meilian Ou,Xiaorui Liu,Zenan Liao,Sheng ChuRSC Adv., 2020,10, 18824-18829 10.1039/D0RA02351E
- [6] An antioxidative galactomannan extracted from Chinese Sesbania cannabina enhances immune activation of macrophage cells? Chongyang Zhu,Xiaojia Bian,Xin Jia,Ning Tang,Yongqiang ChengFood Funct., 2020,11, 10635-10644 10.1039/D0FO02131H
- [7] An aptamer-based keypad lock system? Yaqing Liu,Jiangtao Ren,Jing Li,Jiyang Liu,Erkang WangChem. Commun., 2012,48, 802-804 10.1039/C1CC15979H
- [8] An arsenic trioxide nanoparticle prodrug (ATONP) potentiates a therapeutic effect on an aggressive hepatocellular carcinoma model via enhancement of intratumoral arsenic accumulation and disturbance of the tumor microenvironment? Xin Fu,Qing-rong Liang,Rong-guang Luo,Yan-shu Li,Xiao-ping Xiao,Lu-lu Yu,Wen-zhe Shan,Guang-qin FanJ. Mater. Chem. B, 2019,7, 3088-3099 10.1039/C9TB00349E
- [9] An ATP-selective, lanthanide complex luminescent probe? Xiao Liu,Jun Xu,Yinyun Lv,Wenyu Wu,Weisheng Liu,Yu TangDalton Trans., 2013,42, 9840-9846 10.1039/C3DT50986A
- [10] An integrated droplet-digital microfluidic system for on-demand droplet creation, mixing, incubation, and sorting? Lab Chip, 2019,19, 524-535 10.1039/C8LC01170B
Journal Name：Analyst
research_products
-
CAS no.: 89640-58-4
![1,2,3,4,5,6-Hexahydro-[2,3]bipyridinyl-6-ol](https://ossimg.kuujia.com/scimg/1271000/1270529-38-8x500.png)
![N-(3-cyanothiolan-3-yl)-2-[(2,2,2-trifluoroethyl)sulfanyl]pyridine-4-carboxamide](https://ossimg.kuujia.com/scimg/1444500/1444113-98-7x500.png)
![2,2-Difluoro-3-[methyl(2-methylbutyl)amino]propanoic acid](https://ossimg.kuujia.com/scimg/2138500/2138166-62-6x500.png)
![2-(1H-indol-3-yl)-N-{[6-(thiophen-2-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl]methyl}acetamide](https://ossimg.kuujia.com/scimg/2034500/2034271-14-0x500.png)