Benzothiazepines: chemistry of a privileged scaffold

RSC Advances Pub Date: 2015-08-06 DOI: 10.1039/C5RA12422K

Abstract

Benzothiazepines are one such class of heterocyclic scaffolds with celebrated biological activities. The flooding of the pharmaceutical market with cardiovascular drugs like diltiazem, clentiazem and siratiazem bearing the benzothiazepine core confirms the biological importance of the core. This review presents a comprehensive vision of the various synthetic tactics adopted till now to afford benzothiazepine cores.

Graphical abstract: Benzothiazepines: chemistry of a privileged scaffold
Recommended Literature