A copper-mediated oxidative N-cyanation reaction?
Chemical Communications Pub Date: 2014-06-05 DOI: 10.1039/C4CC03439B
Abstract
Copper-promoted N-cyanation of aliphatic sec-amine by CuCN is achieved via oxidative coupling. This procedure employs O2 as a clean oxidant. Notably, sulfoximines and 1,1,3,3-tetramethylguanidine also worked well in this procedure. Thus, it represents a key progress in the C–N bond formation reaction as well as in the cyanation reaction.
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Journal Name：Chemical Communications
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CAS no.: 89640-58-4
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