Biosynthesis of the angiogenesis inhibitor borrelidin: directed biosynthesis of novel analogues?

Chemical Communications Pub Date: 2006-05-11 DOI: 10.1039/B602931K

Abstract

We report the directed biosynthesis of borrelidin analogues and their selective anti-proliferative activity against human cancer cell lines.

Graphical abstract: Biosynthesis of the angiogenesis inhibitor borrelidin: directed biosynthesis of novel analogues
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