Base-promoted synthesis of dibenzoxazepinamines and quinazolinimines under metal-free conditions?
Green Chemistry Pub Date: 2015-07-27 DOI: 10.1039/C5GC01634G
Abstract
An interesting base-promoted protocol for the synthesis of dibenzo[b,f][1,4]oxazepin-11-amines and quinazolinimines has been developed. Started from commercially available 2-fluorobenzonitriles, 2-aminophenols and 2-aminoethanol, good to excellent yields of the corresponding heterocycles can be achieved. Notably, only K3PO4 or K2CO3 was required as the promoter here and the reaction can be easily performed on a large scale.
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Journal Name：Green Chemistry
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CAS no.: 89640-58-4
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