Identification and molecular genetic analysis of the cichorine gene cluster in Aspergillus nidulans??

MedChemComm Pub Date: 2012-04-17 DOI: 10.1039/C2MD20055D

Abstract

We recently demonstrated that the phytotoxin cichorine is produced by Aspergillus nidulans. Through a set of targeted deletions, we have found a cluster of seven genes that are required for its biosynthesis. Two of the deletions yielded molecules that give information about the biosynthesis of this metabolite.

Graphical abstract: Identification and molecular genetic analysis of the cichorine gene cluster in Aspergillus nidulans
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