Anti-biofilm activity of quinazoline derivatives against Mycobacterium smegmatis?
MedChemComm Pub Date: 2019-05-23 DOI: 10.1039/C9MD00156E
Abstract
Bacteria employ a number of mechanisms to resist the effects of antibiotics, including the formation of biofilms. We explored the anti-biofilm capabilities of a library of compounds based upon a 2-aminoquinazoline (2-AQ) scaffold against Mycobacterium smegmatis. This study resulted in the identification of 2-AQ derivatives with biofilm inhibition activity against M. smegmatis.
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Journal Name:MedChemComm
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CAS no.: 89640-58-4