The ortho : para ratio in aromatic nucleophilic substitution
Journal of the Chemical Society D: Chemical Communications Pub Date: DOI: 10.1039/C29710000069
Abstract
Summary p-Nitrofluorobenzene reacts slightly faster than o-nitrofluorobenzene with methoxide ions in methanol, but under the same conditions the 2-fluorine atom in 2,4-difluoronitrobenzene is replaced faster than the 4-fluorine atom; an explanation is given to reconcile these observations.
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Journal Name:Journal of the Chemical Society D: Chemical Communications
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CAS no.: 89640-58-4