Coupling of L-histidine methyl ester and L-histidine-containing peptide esters to ferric protoporphyrin IX chloride
Journal of the Chemical Society D: Chemical Communications Pub Date: DOI: 10.1039/C29710000369
Abstract
The coupling of L-histidine methyl ester and L-histidine-containing peptide esters to ferric protoporphyrin IX chloride is performed by the mixed carboxylic窶田arbonic acid anhydride method to give the disubstituted products in good yield: spectroscopic evidence indicates that the degree of interaction between the imidazole ligands and the iron atom depends upon the length of the peptide chain.
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Journal Name:Journal of the Chemical Society D: Chemical Communications
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CAS no.: 89640-58-4