Racemisation in peptide synthesis

Journal of the Chemical Society D: Chemical Communications Pub Date: DOI: 10.1039/C29710001588

Abstract

The second-order rate constants for the racemisation of 4-isobutyl-2-phenyl-L-oxazoline-5-one by triethylamine and di-isopropylethylamine in chloroform at 25° were 1400 1 mol–1 min–1 and 113 l mol–1, min–1, respectively.

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