2-Trihalogenomethylbenzazoles. Part I. Formation
Journal of the Chemical Society C: Organic Pub Date: DOI: 10.1039/J39670000020
Abstract
Methods of preparation of 2-trihalogenomethyl-benzimidazoles, -benzothiazoles, and -benzoxazoles have been investigated. It has been shown that the reaction of the mono-salts of o-phenylenediamines, o-aminophenols, and o-aminothiophenols with trichloroacetonitrile or trichloroacetimidate esters affords 2-trichloromethyl substituted benzimidazoles, benzoxazoles, and benzothiazoles. This method has been extended to the preparation of 2-trichloromethyl-2-azolines. A general method of preparation of 2,2′-bibenzimidazolyls is also described.
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Journal Name：Journal of the Chemical Society C: Organic
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CAS no.: 89640-58-4
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