The resolution and absolute configuration of the isomeric 2-dimethylaminocyclohexanols and their derivatives
Journal of the Chemical Society C: Organic Pub Date: DOI: 10.1039/J39690000248
Abstract
The preparation of the enantiomers of cis- and trans-2-dimethylaminocyclohexylacetate methiodide (potential substrates for the enzyme acetylcholinesterase) is reported. The absolute configuration of the cis-enantiomers has been shown from their relationship with compounds of known configuration. The configuration of the trans-enantiomers is inferred from o.r.d. spectral studies.
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Journal Name:Journal of the Chemical Society C: Organic
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CAS no.: 89640-58-4