Quinazoline analogues of folic acid

Journal of the Chemical Society C: Organic Pub Date: DOI: 10.1039/J39700000997

Abstract

Analogues of folic acid having the pteridine ring replaced by quinazoline have been prepared by reductive condensation of appropriately substituted quinazoline-6-carbaldehydes and -carbonitriles with diesters of N-(p-aminobenzoyl) amino-acids, followed by hydrolysis.

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