Purines, pyrimidines, and imidazoles. Part XXXIV. Synthesis and some reactions of N(6)-(formylmethyl)adenine
Journal of the Chemical Society C: Organic Pub Date: DOI: 10.1039/J39700002206
Abstract
N-(6)-(Formylmethyl)adenine has been prepared by careful controlled acidic hydrolysis of N-(6)-(2,2-diethoxyethyl)adenine, and converted into several simple derivatives. More vigorous treatment of the aldehyde with acid gave 5-amino-4(imidazol-2-yl)imidazole, which was converted into imidazo[2,1-i]purine by treatment with diethoxymethyl acetate. The structures of these compounds have been confirmed by chemical and spectroscopic methods and the mechanism of their formation is discussed.
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Journal Name：Journal of the Chemical Society C: Organic
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CAS no.: 89640-58-4
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