B2(OH)4-mediated one-pot synthesis of tetrahydroquinoxalines from 2-amino(nitro)anilines and 1,2-dicarbonyl compounds in water?
Organic Chemistry Frontiers Pub Date: 2017-08-09 DOI: 10.1039/C7QO00604G
Abstract
A practical one-pot synthesis of tetrahydroquinoxalines from readily available 2-amino(nitro)anilines and 1,2-dicarbonyl compounds mediated by diboronic acid with water as both a solvent and a hydrogen donor under metal-free conditions has been discovered. The deuterium labeling experiments with D2O were also performed to demonstrate that water acts as the hydrogen donor.
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Journal Name：Organic Chemistry Frontiers
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CAS no.: 89640-58-4
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