Azomethine-isocyanide [3+2] cycloaddition to imidazoles promoted by silver and DBU?
Chemical Communications Pub Date: 2017-03-13 DOI: 10.1039/C7CC00772H
Abstract
A new silver-promoted [3+2] cycloaddition of azomethine ylides with isocyanides has been described. The methodology provides an efficient and modular approach to 1,2,4-trisubstituted imidazoles of vital bioactive molecules and atypical antipsychotics analogues.
![Graphical abstract: Azomethine-isocyanide [3+2] cycloaddition to imidazoles promoted by silver and DBU](http://scimg.chem960.com/usr/1/C7CC00772H.jpg)
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Journal Name：Chemical Communications
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CAS no.: 89640-58-4
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