Benzoselenadiazole-based responsive long-lifetime photoluminescent probes for protein kinases?
Chemical Communications Pub Date: 2014-02-24 DOI: 10.1039/C3CC49198F
Abstract
Benzoselenadiazole-containing inhibitors of protein kinases were constructed and their capability to emit phosphorescence in the kinase-bound state was established. Labelling of the inhibitors with a red fluorescent dye led to sensitive responsive photoluminescent probes for protein kinase CK2 that emitted red light with a long (microsecond-scale) decay time upon excitation of the probes with a pulse of near-UV light.
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Journal Name：Chemical Communications
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CAS no.: 89640-58-4
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