Regioselectivity in the Hydroboration of Steroidal Δ3-Allylic Alcohols?
Journal of Chemical Research, Synopses Pub Date: DOI: 10.1039/A605946E
Abstract
The presence of an allylic 5α-hydroxy group
in an androst-3-ene increases the proportion of addition of a
borane to the adjacent C-4 compared to the unsubstituted steroid
and directs the addition to the face of the alkene anti
to the hydroxy group with stereochemical effects that may oppose
those of the C-10β-methyl group.
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Journal Name：Journal of Chemical Research, Synopses
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CAS no.: 89640-58-4
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