Asymmetric 1,4-addition of triarylbismuths to enones catalyzed by dicationic palladium(ii) complexes

Chemical Communications Pub Date: 2004-07-20 DOI: 10.1039/B407272C

Abstract

A 1,4-addition of triarylbismuths to cyclic and acyclic enones was carried out in aqueous methanol in the presence of a chiral phosphine–dicationic palladium(II) complex. Palladium complexes of (S,S)-chiraphos or (S,S)-dipamp gave optically active β-arylketones of up to 95% ee.

Graphical abstract: Asymmetric 1,4-addition of triarylbismuths to enones catalyzed by dicationic palladium(ii) complexes
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