Regioselective Base-induced Condensations of Acrylic Acid Derivatives
Journal of Chemical Research, Synopses Pub Date: DOI: 10.1039/A803390K
Abstract
The orientation of cyclization of the reaction of methyl aroylacrylate (1) and aroylacrylic acid (8) with ethyl acetoacetate and/or thiourea leading to the formation of 4-aroylmethylcyclopentane-1,3-dione (2) 5-aryl-3-oxocyclohexene-1,2-dicarboxylic acid (9), 2-imino-5-aroylmethylthiazolidin-4-one (11) and 6-aryl-2-sulfonylpyrimidine-4-carboxylic acid (14) depends on the medium employed; some compounds show moderate antiviral activities against tobacco necrosis virus.
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Journal Name：Journal of Chemical Research, Synopses
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CAS no.: 89640-58-4
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