Tin-mediated Organic Reactions: a Practical Method for the Synthesis of β-Hydroxynitriles and β-Hydroxyketones
Journal of Chemical Research, Synopses Pub Date: DOI: 10.1039/A809418G
Abstract
In the presence of chlorotrimethylsilane, the tin mediated addition of bromoacetonitrile or α-bromacetophenone to aldehydes in THF gives β-hydroxynitriles or β-hydroxyketones in moderate to good yields.
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Journal Name：Journal of Chemical Research, Synopses
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CAS no.: 89640-58-4
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