An economical and green approach for the oxidation of olefins to enones?

Green Chemistry Pub Date: 2004-10-13 DOI: 10.1039/B408974J

Abstract

A new and optimized water-based procedure for the oxidation of steroidal olefins and benzylic compounds to α,β-enones, using household laundry bleach and aqueous tert-butyl hydroperoxide at sub-ambient temperature, is described. This simple methodology is not only economical but is also environmentally friendly. Issues of reactivity, selectivity and scope of the reaction were investigated with a variety of steroidal olefins and benzylic compounds.

Graphical abstract: An economical and green approach for the oxidation of olefins to enones
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