Analysis of mass-limited mixtures using supercritical-fluid chromatography and microcoil NMR

Analyst Pub Date: 2015-07-27 DOI: 10.1039/C5AN00772K

Abstract

A protocol is presented for offline microfluidic NMR analysis hyphenated with supercritical chromatographic separation. The method demonstrates quantitative detection with good sensitivity. Typical sample amounts of 10 nanomoles can be detected in a fast and cost-effective manner.

Graphical abstract: Analysis of mass-limited mixtures using supercritical-fluid chromatography and microcoil NMR
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