Hydrogen-bonded supramolecular polymer micelles with pH/photothermal-responsive carmofur release and combined chemo-photothermal therapy?

Polymer Chemistry Pub Date: 2022-02-05 DOI: 10.1039/D1PY01634B

Abstract

Integrating biomedical applications (e.g., drug delivery) into supramolecular chemistry is a promising strategy. This work targets the construction of hydrogen-bonded (H-bonded) supramolecular polymeric micelles loaded with chemotherapy drugs (carmofur) and photothermal agents (IR780) for combined chemo-photothermal therapies (CT/PTT).

Graphical abstract: Hydrogen-bonded supramolecular polymer micelles with pH/photothermal-responsive carmofur release and combined chemo-photothermal therapy
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