Electrochemical synthesis of dipyrazolo/dipyrimidine-fused pyridines via oxidative domino cyclization of C(sp3)–H bonds?
Organic Chemistry Frontiers Pub Date: 2022-01-31 DOI: 10.1039/D1QO01641E
Abstract
An electrochemically oxidative domino cyclization reaction of methyl azaarenes/ketones with pyrazol-5-amines and 6-amino-pyrimidine-2,4-diones was developed, providing a variety of dipyrazolo[3,4-b:4′,3′-e]pyridines and dipyrimidine-fused pyridines with moderate to good yields. The reaction involved two C–C bond formations and one C–N bond formation in one pot. Moreover, the photoluminescence properties of the representative dipyrazolo[3,4-b:4′,3′-e]pyridines were investigated.
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Journal Name：Organic Chemistry Frontiers
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CAS no.: 89640-58-4
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