The synthetic versatility of fluoroiodomethane: recent applications as monofluoromethylation platform
Organic & Biomolecular Chemistry Pub Date: 2022-05-12 DOI: 10.1039/D2OB00670G
Abstract
In recent years, fluoroiodomethane (CH2FI) has emerged as an easy-to-handle, non-ozone depleting agent and readily available platform for monofluoromethylation strategies. Recent applications in nucleophilic substitutions, lithiation reactions, transition-metal catalyzed transformations, radical processes, and 18F-radiolabelling chemistry showcase the potential of this reagent for the preparation of organofluorine compounds. In this minireview, we provide an update to the field covering the recent relevant literature on the use of CH2FI.
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Journal Name：Organic & Biomolecular Chemistry
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CAS no.: 89640-58-4
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