Expedient synthesis of imino-C-nucleoside fleximers featuring a one-pot procedure to prepare aryl triazoles?
Organic & Biomolecular Chemistry Pub Date: 2023-07-13 DOI: 10.1039/D3OB00956D
Abstract
Nucleoside analogues such as the antiviral agents galidesivir and ribavirin are of synthetic interest. This work reports a “one-pot” preparation of similar fleximers using a bifunctional copper catalyst that generates the aryl azide in situ, which is captured by a terminal alkyne to effect triazole formation.
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Journal Name：Organic & Biomolecular Chemistry
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CAS no.: 89640-58-4
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