Room temperature deoxofluorination of aromatic aldehydes with XtalFluor-E under highly concentrated conditions?
Organic & Biomolecular Chemistry Pub Date: 2023-07-18 DOI: 10.1039/D3OB00859B
Abstract
The synthesis of difluoromethyl-containing compounds exploiting the deoxofluorination reaction of aromatic aldehydes using XtalFluor-E is described. This transformation occurs at room temperature under highly concentrated conditions, i.e., with no added solvent. A wide range of difluoromethyl-containing compounds was obtained in 21 to 87% isolated yields.
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Journal Name：Organic & Biomolecular Chemistry
research_products
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CAS no.: 89640-58-4
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