Stable d-xylose ditriflate in divergent syntheses of dihydroxy prolines, pyrrolidines, tetrahydrofuran-2-carboxylic acids, and cyclic β-amino acids?
Organic & Biomolecular Chemistry Pub Date: 2022-10-26 DOI: 10.1039/D2OB01255C
Abstract
Double nucleophilic displacement of D-xylo-ditriflate by amines, water and alkyl cyanoacetates, respectively, gave a series of bicyclic divergent intermediates for the synthesis of a wide range of highly functionalized targets, including hydroxylated prolines, pyrrolidines, furanoic acids, and cyclopentanes.
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Journal Name：Organic & Biomolecular Chemistry
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CAS no.: 89640-58-4
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