On the evolution of coenzyme biosynthesis?
Natural Product Reports Pub Date: 2022-09-23 DOI: 10.1039/D2NP00037G
Abstract
Covering: up to 2022
The report provides a broad approach to deciphering the evolution of coenzyme biosynthetic pathways. Here, these various pathways are analyzed with respect to the coenzymes required for this purpose. Coenzymes whose biosynthesis relies on a large number of coenzyme-mediated reactions probably appeared on the scene at a later stage of biological evolution, whereas the biosyntheses of pyridoxal phosphate (PLP) and nicotinamide (NAD+) require little additional coenzymatic support and are therefore most likely very ancient biosynthetic pathways.
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Journal Name：Natural Product Reports
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CAS no.: 89640-58-4
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