Electrochemical primary amination of imidazopyridines with azidotrimethylsilane under mild conditions?
Green Chemistry Pub Date: 2022-11-23 DOI: 10.1039/D2GC03703C
Abstract
A straightforward protocol involving electrochemical primary amination of imidazopyridines under mild conditions is described. This transformation utilizes TMSN3 as the nitrogen source and a trace amount of H2O as the hydrogen source. A wide range of imidazopyridines were found to be compatible, providing the corresponding C3-amino substituted imidazopyridines in moderate to good yields.
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Journal Name：Green Chemistry
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CAS no.: 89640-58-4
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