Radical deuteration
Chemical Society Reviews Pub Date: 2022-07-19 DOI: 10.1039/D1CS00907A
Abstract
Deuterated chemicals are becoming irreplaceable in pharmaceutical engineering, material science and synthetic chemistry. Many excellent reviews have discussed acid/base-dependent or metal-catalyzed deuteration reactions, but radical deuterations have been discussed less. With the development of radical chemistry, there has been a rapid growth in radical deuterium-labelling technology. Diverse mild, cheap and efficient strategies for deuterium atom installation have been reported, and this review summarizes the recent achievements of radical deuteration classified by the reaction types.
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Journal Name:Chemical Society Reviews
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CAS no.: 89640-58-4