Engineering a multi-target therapy nanoplatform against tumor growth and metastasis via a novel NSAID-Pt(iv) prodrug?

Chemical Communications Pub Date: 2022-02-21 DOI: 10.1039/D1CC06385E

Abstract

Tumor growth and metastasis are caused by many factors. The complexity means that a multi-target combination therapy strategy should be selected against tumor growth and metastasis. Here, cisplatin (CDDP) and bendazac (Ben) were designed as a novel NSAID-Pt(IV) nanoplatform, which is an effective weapon for combating tumor growth and metastasis.

Graphical abstract: Engineering a multi-target therapy nanoplatform against tumor growth and metastasis via a novel NSAID-Pt(iv) prodrug
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