Electrosynthesis of (hetero)aryl nitriles from α-imino-oxy acids via oxidative decarboxylation/N–O cleavage?
Chemical Communications Pub Date: 2022-07-12 DOI: 10.1039/D2CC02986C
Abstract
A new method for the synthesis of (hetero)aryl nitriles via iminyl radicals has been developed through the electrochemical oxidative decarboxylation of α-imino-oxy acids. This protocol provides an efficient approach to nitriles with a broad range of functional-group tolerance under ambient conditions and can be applied for one-pot gram-scale synthesis.
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Journal Name：Chemical Communications
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CAS no.: 89640-58-4
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