Formation of carotenoid supramolecular aggregates in nanocarriers monitored via aggregation-sensitive chiroptical output of enantiopure (3S,3′S)-astaxanthin?
Chemical Communications Pub Date: 2022-07-25 DOI: 10.1039/D2CC02649J
Abstract
The aggregation-sensitive chiroptical (ECD and RROA) output, provided by enantiopure (3S,3′S)-astaxanthin, was used to investigate and control the assembling processes of the carotenoid in Pluronic F-127 nanoparticles. The process of carotenoid J-aggregation inside nanocarriers is interfered with by the formation of kinetically stabilized H1 self-assemblies outside the micelles. Nanocarriers with encapsulated stable J-aggregates provide controlled release of carotenoid molecules to primary murine adipocytes.
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Journal Name：Chemical Communications
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CAS no.: 89640-58-4
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