Synthesis of highly substituted isoquinolines/isoquinolones by ruthenium (ii)-catalyzed reaction of benzyl/α-methyl benzyl/benzoyl isocyanates with diaryl alkynes?
Chemical Communications Pub Date: 2023-02-20 DOI: 10.1039/D2CC06165A
Abstract
An efficient and novel method has been developed for the synthesis of highly substituted isoquinolines/isoquinolones by Ru(II)-catalyzed intermolecular oxidative annulation of benzyl/benzoyl isocyanates with diaryl alkynes in the presence of Cs2CO3 as base and Cu(OTf)2 as an oxidant at 120 °C for 1 h.
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Journal Name：Chemical Communications
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CAS no.: 89640-58-4
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