H2O2-driven enzymatic oxyfunctionalization of tertiary C–H bonds?
Chemical Communications Pub Date: 2023-07-03 DOI: 10.1039/D3CC02925E
Abstract
Peroxygenase from Agrocybe aegerita catalyses the selective hydroxylation of tertiary C–H bonds, whereby tertiary alcohols, diols, ketols, etc., were obtained in good to high regioselectivity and turnover numbers. This method can also be expanded for late-stage functionalization of drug molecules, which represents a streamlined synthetic method to give access to useful compounds.
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Journal Name：Chemical Communications
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CAS no.: 89640-58-4
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